Hyperthyroidism refers to an overactive thyroid (when it produces too much thyroid hormone) and hypothyroidism refers to an underactive thyroid (when it does not produce enough). These two conditions often have different signs and symptoms. But sometimes the symptoms can overlap. Robert Graves (1796–1853) is fundamentally recollected for his clinical portrayal of Graves’ illness of the thyroid organ. In 1834 at the Meath Healing center, Dublin, he commented ‘I have recently seen three cases of savage and long proceeded palpitations in females, in each of which the same quirk displayed itself – viz. broadening of the thyroid organ; the measure of this organ, at all times more noteworthy than characteristic.