Journal of Clinical and Molecular Endocrinology

Application of Nano-biotechnology for Improvement in Therapeutic Approaches for the Treatment of Diabetes

Diabetes mellitus is a chronic metabolic disorder which results in elevated blood glucose. It can be broadly classified as Type 1 and Type 2, depending on the reason for the high blood glucose levels. In Type 1 diabetes enough insulin is not produced by pancreatic beta cells, whereas in Type 2 the body's cells poorly respond to the presence of insulin. Nanotechnology holds a great deal of promise in diabetes management for efficient drug delivery, generation of smart drugs which only activate when needed. Anti-diabetes therapy is significantly transformed by using nanotechnology in many ways like in delivery of therapeutic molecules, fabrication of nanosensors to monitor dynamic changes in blood glucose level, and development of smart imaging molecule to visualise and quantify beta cells etc. This review article explores the way in which nanotechnology could be used to effectively treat, and possibly cure, diabetes. We anticipate in the long run, nanotechnology will clearly open up many routes to treatments and participate in understanding and finding a cure that would improve the lives of all people affected by diabetes.

Author(s):

Mukhopadhyay A, Prosenjit M

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